By Arthur Weil (Auth.)
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Area of pyramidal tract is unstained F I G . 5 0 . SECONDARY A S C E N D I N G D E G E N E R A T I O N OF G O L L ' S C O L U M N S Following destruction of lumbar vertebrae and compression of spinal cord by prostate cancer metastases. Transverse section through ninth dorsal segment. Weil stain. Unstained area in posterior columns corresponds to nerve fibers originating in spinal cord segments from sixth sacral to first lumbar m a t e l y one m o n t h after the lesion, the water was decreased b y 14 per cent and the total phosphorus b y one-third, while the water-soluble phosphorus was increased b y 35 per cent ( M a y ) .
In the glia stars and nodules the single glia cell preserves its individuality (fig. 4 1 ) . T h e final step in neuronophagia and star formation seems t o b e the gradual disappearance of the c o m p o u n d granular corpuscles that participated, leaving behind only a fine fibrous tissue; or they m a y themselves degenerate, breaking d o w n before the process of repair has been definitely finished, as in the plaques of senile brains, in which the vitality of the c o m p o u n d granular corpuscles that try t o invade dead tissue seems 40 NEUROPATHOLOGY also t o have suffered (fig.
H o w e v e r , m o r e recently w e have learned that such different shades of staining are due t o the p H of the tissue as determined b y postmortem and fixation conditions. Therefore the idea of staining with aniline dyes in buffer solutions at a given pH (thionin staining as devised b y F I G . 55. D E G E N E R A T I O N OF A X I S - C Y L I N D E R S Neighborhood of hemorrhagic F I G . 56. softening. Davenport stain. bulb formations Loop, spiral, and D E G E N E R A T I O N OF A X I S - C Y L I N D E R S Status spongiosus in brain of dog after experimental ligation of common bile duct.