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Microglia Biology, Functions and Roles in Disease by Charanjit Kaur, Ling Eng-ang

24 February 2017 adminCell Biology

By Charanjit Kaur, Ling Eng-ang

The pioneering experiences via a number of major researchers within the early a part of the final century first defined the lifestyles of microglial cells either within the early mind improvement and in pathological stipulations. Microglial cells have been later confirmed to be the resident mind macrophages and immunocompetent cells current ubiquitously within the imperative worried method together with the retina in organization with different glial cells, neurons and blood vessels. The e-book may be of curiosity to phone biologists and neuroscientists typically. easy scientists, neuroimmunologists, neurologists, neuropathologists and neurosurgeons should still locate the most recent details on microglial cells valuable of their persisted attempt in looking and designing capability healing suggestions for therapy of neurological sickness for which microglial cells are implicated.

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Microglia Biology, Functions and Roles in Disease

The pioneering reports via a number of major researchers within the early a part of the final century first defined the life of microglial cells either within the early mind improvement and in pathological stipulations. Microglial cells have been later demonstrated to be the resident mind macrophages and immunocompetent cells current ubiquitously within the relevant worried process together with the retina in organization with different glial cells, neurons and blood vessels.

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Extra resources for Microglia Biology, Functions and Roles in Disease

Sample text

Kooijman R. Regulation of apoptosis by insulin-like growth factor (IGF)-I. Cytokine Growth Factor Rev. (2006) 17:305-323. Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, Shibuya M, Saya H, Suda T. M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J. Exp. Med. (2009) 206:1089-1102. Kuno R, Wang J, Kawanokuchi J, Takeuchi H, Mizuno T, Suzumura A. Autocrine activation of microglia by tumor necrosis factor-alpha. J. Neuroimmunol. (2005) 162:89-96. Laskey J, Webb I, Schulman HM, Ponka P.

Neuroscience (2006a) 138:1233-1244. Kaur C, Sivakumar V, Ang LS, Sundaresan A. Hypoxic damage to the periventricular white matter in neonatal brain: role of vascular endothelial growth factor, nitric oxide and excitotoxicity. J. Neurochem. (2006b) 98:1200-1216. Kawanokuchi J, Mizuno T, Takeuchi H, Kato H, Wang J, Mitsuma N, Suzumura A. Production of interferon-gamma by microglia. Mult. Scler (2006) 12:558-564. Kielian T, Mayes P, Kielian M. Characterization of microglial responses to Staphylococcus aureus: effects on cytokine, costimulatory molecule, and Toll-like receptor expression.

Ann. Neurol. (2005) 57:6781. Vezzani A, Ravizza T, Balosso S, Aronica E. Glia as a source of cytokines: implications for neuronal excitability and survival. Epilepsia (2008) 49 Suppl 2:24-32. Vincent VA, Tilders FJ, Van Dam AM. Production, regulation and role of nitric oxide in glial cells. Mediators Inflamm (1998) 7:239-255. Volpe JJ. Neonatal encephalitis and white matter injury: more than just inflammation? Ann Neurol (2008) 64:232-236. Wang CC, Wu CH, Shieh JY, Wen CY, Ling EA. Immunohistochemical study of amoeboid microglial cells in fetal rat brain.

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