By Visith Thongboonkerd
The hot improvement of proteomics reports into medical examinations of proteomics supplies to steer towards the final word targets of prior prognosis, more desirable healing consequence and winning prevention of illnesses. In Proteomics of Human Bodyfluids: rules, tools, and functions, best specialists give you the ultimate number of proteomics functions designed to investigate a number of human physique fluids. starting with simple rules and methods then exploring methodologies, fresh findings, and medical functions, this authoritative quantity covers its topic in nice element from many angles. finished and huge, Proteomics of Human Bodyfluids: rules, tools, and functions is a perfect reference for all scientists drawn to this important, transforming into box of analysis.
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Extra resources for Proteomics of Human Bodyfluids: Principles, Methods, and Applications
Sample text
50. Zuo X, Speicher DW. A method for global analysis of complex proteomes using sample prefractionation by solution isoelectrofocusing prior to two-dimensional electrophoresis. Anal Biochem 2000;284:266–278. 51. Zuo X, Speicher DW. Microscale solution isoelectrofocusing: a sample prefractionation method for comprehensive proteome analysis. Methods Mol Biol 2004;244:361–375. 52. Tang HY, Ali-Khan N, Echan LA, Levenkova N, Rux JJ, Speicher DW. A novel four-dimensional strategy combining protein and peptide separation methods 28 53.
Efficiency (A) and selectivity (B) of albumin removal from human serum using an antialbumin immunoaffinity column. 6 × 105). 3 (doubly charged molecular ion of peptide IVDLVK; positions 193–198 in human α1-antitrypsin) of tryptic digests of human serum (upper trace; peak height 16,052) or of human serum after depletion with an antialbumin immunoaffinity column (lower trace; peak height 32,607). Note the much cleaner detection of this peptide fragment after depletion and the increased overall peak height.
Proteomics 2002;2:1652–1657. Hoffmann P, Ji H, Moritz RL, et al. Continuous free-flow electrophoresis separation of cytosolic proteins from the human colon carcinoma cell line LIM 1215: a non two-dimensional gel electrophoresis-based proteome analysis strategy. Proteomics 2001;1:807–818. Krivankova L, Bocek P. Continuous free-flow electrophoresis. Electrophoresis 1998;19:1064–1074. Weber PJA, Weber G, Eckerskorn C. Protein purification using free-flow electrophoresis. In: Simpson RJ, ed. Purifying Proteins for Proteomics: A Laboratory Manual.