By Afaf Kamal-Eldin, David Min
This quantity enhances Lipid Oxidation Pathways, quantity 1 via targeting the oxidation kinetics and mechanisms governing the habit of other molecular species fascinated about lipid oxidation reactions. It offers a extra specific evaluate of the reactions of different lipid molecules than traditional polyunsaturated fatty acids.
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Extra info for Lipid Oxidation Pathways, Volume Two
Example text
The 3CAR can easily return to the 1CAR dissipating energy as a heat. 4 kcal/mole) is exothermic (Foote, 1970). J. B. Min effective at quenching triplet chlorophyll. Carotenoids with fewer than nine conjugated double bonds have energies above that of singlet oxygen and are less efficient singlet oxygen quenchers. Carotenoids with eleven or more conjugated double bonds quench at a diffusion-controlled rate of singlet oxygen. The rate of singlet oxygen quenching by carotenoids is dependent on the number of conjugated double bonds and the type and number of functional groups on the ring portion of the molecule.
This is called tocopherol-mediated peroxidation (Bowry and Stocker, 1993; Yamamoto 2001). 83 x 10-2 M-1s-1 at 25oC, respectively (Mukai and Okauchi, 1989). , 2002). Ascorbic acid prevents tocopherol-mediated peroxidation by reducing the tocophroxyl radical to tocopherol (Yamamoto, 2001). Chemistry and Reactions of Reactive Oxygen Species in Lipid Oxidation 41 CH3 HO CH3 H 3C O C H 2 (C H 2 C H 2 CH3 CH3 C H C H 2)3 H + ROO + ROOH (T O H ) CH3 O CH3 H 3C O CH3 C H 2 (C H 2 C H 2 CH3 C H C H 2)3H (T O ) + R 'O O + TO CH3 toco p h e ro l dim e r O CH2 O H 3C CH2 CH3 (C H 2 C H 2 C H C H 2 ) 3 H CH3 to copherol se m iqu ino ne Fig.
At every stage in this reaction, there is at least one alternate route, which, if taken, would minimize the oxidation of the compound (A). The first step represents Sen hv 1 Sen* KISC 3 3 Sen* Q O2 ko 1 Q kq kQ A kr O2 AO2 kd Q kox-Q 3 1 Sen Sen O2 3 QO2 O2 Fig. 13. Formation of singlet oxygen and its reaction with substrate a to produce the oxidized product AO2. the return of the 1Sensitizer* to 1Sensitizer without intersystem crossing which can form the3Sensitizer*. The second represents a reaction with a quencher (Q) at a rate KQ, returning the 3Sensitizer* to 1Sensitizer prior to reaction with triplet oxygen.