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Atherosclerosis: Molecular and Cellular Mechanisms by Sarah Jane George, Jason Johnson

24 February 2017 adminCell Biology

By Sarah Jane George, Jason Johnson

Protecting the main devastating disorder within the Western global, this guide and prepared reference offers a complete account of the various levels and components within the improvement of the atherosclerotic plaque. every one bankruptcy is written by way of specialists within the box and highlights the function of particular mediators of atherosclerotic plaque improvement, in addition to strength healing objectives. a large number of this up to date details is conveyed in terms of tables and schematic figures, in a without problems understandable demeanour. a must have for grasp and PhD scholars, researchers, MDs and academics in vascular biology and cardiology, in addition to for lecturers and scientists within the pharmaceutical undefined.

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Additional resources for Atherosclerosis: Molecular and Cellular Mechanisms

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Soc. , 34 (Pt 3), 422–426. M. (2006) Oxidized lipiddriven chemokine receptor switch, CCR2 to CX3CR1, mediates adhesion of human macrophages to coronary artery smooth muscle cells Through a peroxisome proliferator-activated receptor γ-dependent pathway. Circulation, 114 (8), 807–819. , et al. (1999) MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J. Clin. , 103 (6), 773–778. F. (1998) Decreased lesion formation in CCR2−/− mice reveals a role for chemokines in the initiation of atherosclerosis.

Eur. , 25 (16), 1447–1453. , et al. (2004) Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc. Natl Acad. Sci. U. S. , 101 (29), 10679–10684. K. (2008) Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events. J. Exp. , 205 (2), 373–383. K. (2005) Modulation of atherosclerosis in mice by Toll-like receptor 2. J. Clin. , 115 (11), 3149–3156.

2004) Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease. Trends Cardiovasc. , 14, 323–327. , et al. (2009) Heme oxygenase-1 expression enhances vascular endothelial resistance to complement-mediated injury through induction of decay-accelerating factor: a role for increased bilirubin and ferritin. Blood, 113 (7), 1598–1607. , et al. (2007) Heme oxygenase-1 deficiency accelerates formation of arterial thrombosis through oxidative damage to the endothelium, which is rescued by inhaled carbon monoxide.

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