By P.H. Jongbloet
Parents of youngsters born with psychological or actual handicaps, are inclined to face the health care professional with questions on the foundation of the abnormality involved and the opportunity of getting one other baby with an analogous . The health care provider then unearths himself in a tough scenario because the factors of the vast majority of congenital abnormalities stay as but unknown. usually he has to limit himself to an insignificant enumeration of the symptoms encountered or, at top, to a type of the syndrome to hand. Efforts are usually made to attach either the somatic aberrations and the psychological deficiency with issues through the later phases of being pregnant, on the time of supply or within the rapid postnatal interval. even if, a cautious look for such goods as irregular dermatoglyphs, or 'degenerative stigmata', and, particularly, a autopsy exam of the mind, frequently exhibits that the handicap involved might be ascribed to elements working lengthy prior to the time of delivery. Theoretically, the motives of abnormalities current at delivery could be indexed as of a genetic, germinal or peristatic nature. in the past a long time detailed awareness has been paid to either genetic and peristatic elements. the aim of this thesis is to emphasize the significance of germinal elements, particularly these which, at the very least in idea, may perhaps result in disturbances within the ripening technique of the human egg. We have been wear this music through a few info about the situations below which one in all our sufferers possibly have been conceived.
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Mental and Physical Handicaps in connection with Overripeness Ovopathy
Mom and dad of kids born with psychological or actual handicaps, are inclined to face the health practitioner with questions about the starting place of the abnormality involved and the opportunity of getting one other baby with an identical situation. The general practitioner then reveals himself in a tough scenario because the motives of the vast majority of congenital abnormalities stay as but unknown.
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Additional info for Mental and Physical Handicaps in connection with Overripeness Ovopathy
Example text
Hamers are thanked for their metabolic and cytogenetical investigations, Mrs. G. A. van der Meij, B. , for the translation into English and Mrs. E. Lely-van Baal for drawing the diagrams. SUMMARY To test the hypotheses formulated earlier concerning the overripeness of the egg we questioned I27 couples with one or more mentally retarded children to enquire after the time and circumstances under which conception took place. Attention was paid to all pregnancies, whether or not resulting in an abortion, a mentally retarded or a normal child.
BARTZEN, P. , Effectiveness of the Temperature Rhythm-system of contraception. Fertil. Steri/. 18: 694, 1967. BELL, E. T. and]. A. LORAINE, Time of ovulation in relation to cycle length. Lancet, I: 1029, 1965. , G. K. DORING and C. HOSSFELD, Experimentelle Friihovulation durch Cervixreizung beim Menschen. Archiv for Gynakol. 192: 412, 1960. BnID, A. , Anticonvulsant drugs and congenital abnormalities. Lancet, i: 3II, 1969. BoUB,]. ,J. COHEN,J. HENRy-SUCHET, R. MERGER and C. VINCENT, Etude c1inique et biologique de 16 cas d'avortements spontanes par aberration chromosomique.
In a previous investigation of these phenomena, parents of mentally retarded children from our institute were used to furnish starting material. A clear relationship was found between a "positive overripeness anamnesis" and the production of physically and mentally retarded progeny with or without chromosomal aberrations. Consequently, we suggested that the population of an institute like ours is in fact a collection of the results of conception pathology in the normal population. To test this hypothesis, an investigation was performed in a population that was randomly chosen from the towns of Cuyk and Nijmegen.