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[Magazine] Scientific American. Vol. 275. No 1

24 February 2017 adminNonfiction 3

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Extra resources for [Magazine] Scientific American. Vol. 275. No 1

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It was not until late in 1992 that researchers from the Brown-Purdue group and, independently, from Sony found a way around the dilemma. The solution involves a graded alloy of ZnSe and ZnTe that replaces the sharp barrier to conduction between the metal and ZnSe with a gentle incline. Most research worldwide now focuses on increasing the lifetime of continuously operated II-VI semiconductor blue and green diode lasers and on improving the quality of the nitride compound materials. 0 BAND-GAP ENERGY IN ELECTRON VOLTS BAND-GAP ENERGY of a semiconductor crystal determines the energy of the photons it emits and thus the wavelength of the light those photons produce.

J. Halper and J. , Vol. 88, No. 22, pages 10124 –10128; November 15, 1991. Sunburn and p53 in the Onset of Skin Cancer. A. Ziegler, A. S. Jonason, D. J. Leffell, J. A. Simon, H. W. Sharma, J. Kimmelman, L. Remington, T. Jacks and D. E. Brash in Nature, Vol. 372, pages 773–776; December 22–29, 1994. Cancer Free: The Comprehensive Cancer Prevention Program. Sidney J. Winawer and Moshe Shike. Simon & Schuster, 1996. Sunlight, Ultraviolet Radiation and the Skin. NIH Consensus Statement. Vol. 7, No.

A Signature Mutation T hat search was daunting. The DNA in a human cell contains as many as 100,000 genes, and each gene typically includes thousands of nucleotides (the building blocks of DNA)—only some of which would be likely to bear traces of sun-induced damage. And even if we managed to identify mutations in skin cancer samples, how could we be sure that sunlight had caused them? Fortunately, other investigators had given us a useful clue by finding that ultraviolet B radiation—long suspected to be the carcinogenic factor in sunlight—had a characteristic signature.

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