By Quinn, Graham; Fielder, Alistair
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Geneva (Switzerland): World Health Organisation; 2012. 75. Dandona R, Dandona L. Childhood blindness in India: a population based perspective. Br J Ophthalmol 2003;87(3):263–5. 76. Nations U. The Millennium Development Goals report 2012. New York: United Nations; 2012. 77. Victora CG, Aquino EM, do Carmo Leal M, et al. Maternal and child health in Brazil: progress and challenges. Lancet 2011;377(9780):1863–76. 78. Barros FC, Victora CG, Barros AJ, et al. The challenge of reducing neonatal mortality in middle-income countries: findings from three Brazilian birth cohorts in 1982, 1993, and 2004.
Ten countries account for 60% of all preterm births. 74 The presence of the United States on this list may reflect economic differences between racial groups as well as regional differences regarding access to neonatal care. 2 The decrease of IMR is the fourth goal of the Millennium Development Goals (MDGs), the UN’s action plan to raise the world’s population out of extreme poverty, and its consequences, by 2015. 78 These nonmedical reasons for inducing delivery particularly cause an increase in birth rates of moderately premature infants (32–37 weeks’ GA),56 which is the high-risk group for ROP in middle-income countries.
1). 23,29,30 Animal models of OIR have been developed in the neonatal kitten, dog, rat, and mouse. The mouse OIR model is currently the most commonly used model as it is reproducible, can be reliably quantified, and can be manipulated genetically (Fig. 21,22,30–37 Fig. 1. Treatment of ROP is based on understanding pathogenesis. (1) Laser photocoagulation of ROP: hypoxic retina anterior to neovascularization in phase II of ROP, which produces VEGF, and Epo is destroyed to decrease pathologic blood vessel formation (promoting C to D).