By J.H.U. Brown, James Francis Dickson
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Time Domain Example II: Nitrogen Washout The time course of nitrogen elimination from the lungs following a step inhalation of pure oxygen has been used for over 25 years as an index of pulmonary function (Robertson et ai, 1950; Fowler et ai, 1952). The major phenomenon involved is simple dilution, which for a single uniform com partment is simply described by a first-order differential equation. However, the lungs are composed of a large number of parallel pathways each with a different volume and ventilation, which complicates interpretation.
The major phenomenon involved is simple dilution, which for a single uniform com partment is simply described by a first-order differential equation. However, the lungs are composed of a large number of parallel pathways each with a different volume and ventilation, which complicates interpretation. Since multiple-dilution pathways lead to exponential processes, it is natural to apply the "backward-projection" technique for graphical separation of com partments based on semilogarithmic plots.
One may observe at this point that after the original artwork has been prepared it is largely immaterial whether a given pattern corresponds to a single transistor or to a complex integrated circuit containing several hundred to several thousand transistors and related circuit elements. The photo graphic reduction and subsequent utilization of a set of masks are virtually identical procedures for both cases. The most significant difference may be the number of patterns that can be contained within a given area of a final reduction plate and hence the number of integrated circuit chips in a given area of a silicon wafer.