By E Y Adashi; P C K Leung
This authoritative and modern reference offers the main updated medical and theoretical info to be had on ovarian body structure. greater than seventy five of the world's best specialists in pertinent scientific and examine components research all levels of the ovarian existence cycle, synthesizing molecular and mobile aspect with classical body structure and pathophysiology in a hugely prepared demeanour. assurance starts off with a close description of the follicular gear and its legislation, after which strikes directly to oocyte maturation, ovulation, and corpus luteum formation. designated emphasis is put on cyclic ovarian mobilephone loss of life, a side of ovarian body structure now coming to the fore. shut awareness is additionally given to intraovarian legislation through development components, cytokines, hormones, and regulatory peptides. a bit on pathophysiology comprises a well timed dialogue on ovulation induction and gonadotropin remedy
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Extra resources for The Ovary
Sample text
1986). Gene transfer and molecular cloning of the human NGF receptor. Science 232, 518–521. Barrett, G. L. (2000). The p75 neurotrophin receptor and neuronal apoptosis. Prog. Neurobiol. 61, 205–229. Dobrowsky, R. , Jenkins, G. , and Hannun, Y. A. (1995). Neurotrophins induce sphingomyelin hydrolysis. J. Biol. Chem. 270, 22135–22142. Hantzopoulos, P. , Glass, D. , Goldfard, M. , and Yancopoulos, G. D. (1994). The low-affinity NGF receptor, p75, can collaborate with each of the trks to potentiate functional responses to the neurotrophins.
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Metab. 5, 317–323. 4 Detection of trkA (green label) and p75m'R (red label) immunoreactive material in infantile (7-dayold) ovaries from wild-type and NGF - / - mice by immunohistofluorescence-confocalmicroscopy. Cell nuclei stained with the vital dye Hoechst are shown in blue. A, Detection of trkA positive cells in interstitial cells, prethecal cells of secondary follicles (arrowheads), and in subsets of granulosa cells in the same follicles (ovary from a wild-type animal). p75NTR-positive cells are mostly confined to the interstitial-prethecal compartments of the ovary.