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Epigenetics, the Environment, and Children’s Health Across by David Hollar

24 February 2017 adminWomens Health

By David Hollar

This stimulating quantity addresses very important questions about gene/environment interactions as they have an effect on cellphone well-being from the prenatal interval via later lifestyles. starting with a travel of epigenetic procedures within the human physique, the booklet assembles present theoretical and empirical advancements around the self-discipline, between them transgenerational epigenetic inheritance, the consequences of maternal nutrients on epigenetic swap, and attainable hyperlinks among epigenetics and youth weight problems. Public future health and coverage features of the sector are mentioned intensive, with the certainty that a lot could be performed to enhance our epigenetic overall healthiness as a species. And during this vein, individuals contemplate destiny chances, akin to the reprogramming of genes to opposite melanoma and different illnesses.

Included within the coverage:

  • The position of environmental epigenetics in perinatal and neonatal development
  • The epigenetic biomarker γH2AX: from bench technological know-how to scientific trials
  • What’s the chance? Dental amalgam, mercury publicity, and human health and wellbeing hazards during the lifespan
  • Post-traumatic tension illness: neurological, genetic, and epigenetic bases
  • Children’s publicity to alcohol, tobacco, and medication: long term outcomes
  • Ethical implications of epigenetics

Epigenetics, the surroundings, and Children’s well-being throughout Lifespans brings real-world wisdom and functions of this more and more vital box to public well-being practitioners, maternal and baby future health researchers, and environmental future health experts.

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Extra info for Epigenetics, the Environment, and Children’s Health Across Lifespans

Example text

J. (2007). Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis. Human Molecular Genetics, 16, R88–R95. -H. (2008). DNA methylation: A two-edged sword as a target for anti-cancer drugs. Bioscience Hypotheses, 1(6), 334–335. Davies, P. C. , & Tuszynski, J. A. (2011). Cancer as a dynamical phase transition. Theoretical Biology and Medical Modeling, 8, 30. 1186/1742-4682-8-30. , et al. (1978). Cell lineages of the embryo of the nematode Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America, 75, 376–380.

Meyerowitz, E. (1998). Principles of development. New York: Oxford University Press. W. Holler Jr. , Martin, J. , & Senthilselvan, A. (2015). Association between lung function in adults and plasma DDT and DDE levels: Results from the Canadian Health Measures Survey. Environmental Health Perspectives, 123(5), 422–427. , & Bierer, L. (2009). The relevance of epigenetics to PTSD: Implications for the DSM-IV. Journal of Trauma and Stress, 22(5), 427–434. , Feinberg, A. , et al. (2008). Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA.

1007/978-3-319-25325-1_2 21 22 M. Georgieva et al. telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. Deep understanding of these common aging features could be a major step toward development and application of specific pharmaceutical approaches, the aim of which would be to ameliorate, slow, and successfully manipulate the process of getting old.

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